Route 1 Gaziantep - Halfeti - Adıyaman
Zeugma Mosaic Museum, Gaziantep Castle, Coppersmiths' Bazaar, Belkıs/Zeugma Ancient City, Karkamış Ancient City, Halfeti boat tour and Adıyaman accommodation
Route 2 Nemrut Sunrise - Şanlıurfa - Harran - Balıklıgöl
Mount Nemrut and sunrise, Traditional Harran Houses, Şanlıurfa Archeology Museum, Balıklıgöl, Soğmatar Ancient City, Vernacular domed houses of Harran and Balikligol
Route 3 Göbeklitepe
Göbeklitepe open air museum
Route 4 Mardin-Midyat
Mardin houses and narrow streets, Mardin Museum, The Grand Mosque, Zinciriye Madrasa, Mor Behnam Church, Kasımiye Madrasa, Deyrulzafaran Monastery, Dara Ancient City, Midyat, Midyat Guest House, Mor Gabriel Monastery and Historical Bazaar
Route 5 Diyarbakır
Hasanpaşa Inn, Dört Ayaklı Minaret (Sheikh Mutahhar Mosque), Grand Mosque, On Gözlü Bridge, Dicle (On Gözlü) Bridge and Saharan Glass located on the bridge, Keçi Bastion